Platelet-derived growth factors (PDGF) are naturally occurring proteins in the body known for their critical role in cellular growth, tissue repair, and wound healing. By promoting the proliferation of fibroblasts and endothelial cells, PDGF plays a key role in the production of collagen and elastin—two essential components for maintaining youthful, healthy skin.

Pure PDGF is a recombinant PDGF and is the only growth factor with four FDA-approvals.  It has been utilized therapeutically for various treatments including orthopedic and maxillofacial surgery applications in over five million patients over the past 15 years.

Ariessence Pure PDGF+ utilizes a bioidentical, lab-derived form of PDGF that delivers consistent and highly effective results. This innovative product eliminates the need for invasive procedures that include blood draws, offering a more convenient and accessible approach to skin rejuvenation.  The PDGF in Ariessence is produced using an FDA-approved manufacturing process that results in a sterile and pure version of PDGF with no mRNA or DNA in the product.

Ariessence Pure PDGF+ stimulates the body’s natural repair processes. Once applied, it binds to specific receptors on the surface of skin cells, triggering a cascade of biological responses:

• Fibroblast activation: Encourages the production of collagen and elastin, which are vital for skin firmness and elasticity.

• Angiogenesis: Promotes the formation of new blood vessels, improving nutrient delivery and overall skin health.

• Cell proliferation: Stimulates the growth of new skin cells, aiding in repair and rejuvenation.

• Tissue remodeling: Enhances the skin’s ability to recover from damage and maintain a youthful structure.

Ariessence provides a wide range of skin benefits that include:

• Improved skin texture: Stimulates collagen and elastin production, leading to smoother, firmer skin.

• Reduction in fine lines and wrinkles: Enhances skin elasticity and reduces the appearance of signs of aging.

• Accelerated wound healing: Speeds up the repair process for damaged skin, making it ideal for post-procedure recovery.

• Minimized scarring: Promotes even skin regeneration, reducing the visibility of scars.

• Increased hydration: Encourages the formation of a healthy skin barrier, improving moisture retention.

• Brightened complexion: Improves cell turnover for a radiant and even skin tone.

• Hair growth and strengthening: When utilized on the scalp, PDGF is proven to enhance hair growth while making boosting hair strength and thickness

Ariessence treatments can be performed in several ways:

• In conjunction with microneedling on the face, with benefits including improvement of the texture of the skin, reduction of lines, pore size, wrinkles and scarring, and a brightened complexion.

• In conjunction with microneedling on the scalp to encourage hair growth and boost hair strength and thickness.

• Applied topically following radiofrequency microneedling treatment to reduce downtime.

Ariessence Pure PDGF+ is suitable for a wide range of individuals looking to improve the health and appearance of their skin or hair. Ideal candidates include:

• Those seeking to reduce fine lines, wrinkles, or scars.

• Individuals with dull, uneven skin tone or texture.

• Patients looking to enhance the results of microneedling or laser treatments.

• People who want a non-invasive alternative to PRP treatments.

• People looking to boost the strength and growth of hair on the scalp.

Traditional PRP treatments require drawing the patient’s blood, isolating the platelet-rich plasma by spinning the blood in a centrifuge, and then applying it to the skin. While PRP is effective, the process can be time-consuming, invasive, inconsistent depending on the patient’s blood, and uncomfortable for some patients.

Ariessence Pure PDGF+ eliminates the need for a blood draw. Instead of relying on the patient’s platelets, the product contains a laboratory-engineered version of PDGF. PDGF+ is pharmaceutical-grade and every lot is the same – pure, potent, predictable, sterile, and safe. By removing the dependency on patient-derived materials, Ariessence Pure PDGF+ offers a more standardized approach to achieving optimal results, with a consistent concentration that contains up to 300,000 more growth factors per application than PRP.

For optimal results, multiple treatments may be recommended by your physician or provider. Many patients undergo a series of 3 to 6 treatments spaced 4 to 6 weeks apart. The exact number of sessions depends on individual skin concerns and goals.

Patients often notice an improvement in skin texture and hydration within a few days of treatment. However, the most significant results, such as reduced wrinkles and improved firmness, typically become visible after 4 to 8 weeks as collagen production increases. Continued improvements can be seen for several months post-treatment.

For scalp treatments, patients often notice improvements in the strength of the hair within a month.

Results from Ariessence Pure PDGF+ can last anywhere from 6 months to a year, depending on the patient’s skin condition and maintenance routine. Regular follow-up treatments and a good skincare regimen can help prolong the benefits.

One of the advantages of Ariessence treatments is the minimal downtime involved. Patients may experience mild redness, swelling, or sensitivity immediately after the procedure, but these side effects usually subside within 24 to 48 hours. Most individuals can resume their daily activities the day after treatment.

Ariessence treatments are generally well-tolerated with minimal risk for adverse effects. Common side effects include temporary redness, swelling, or slight discomfort, which resolve quickly.